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Chen L, Deng H, Cui H et al (2018) Inflammatory responses and inflammation-associated diseases in organs

Collagen turnover, skin barrier integrity, and fibroblast activity vary based on age, genetics, and inflammatory state

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Vitamin B12, or cobalamin, is key for many body functions

As noted previously, the EGR assay is invalid for persons with glucose6- phosphate dehydrogenase deficiency

Current therapeutic strategies for these conditionssuch as oral small-molecule drugs, systemic chemotherapy, or surgical intervention are often constrained by limitations, including poor targeting efficiency, rapid drug degradation, significant off-target side effects, and difficulty in penetrating diseased tissues (e.g., tumor stroma or inflamed mucosa) [7, 8]