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Microscopy and gross anastomosis assessment Parameters assessed Massive small bowel resection Massive small bowel resection Diclofenac saline BPC157 g saline BPC157 g BPC 157 ng L-NAME L-arg L-NAME +L-arg L-NAME +BPC 157g L-arg +BPC 157 g L-NAME+L- arg+BPC 157g Edemascored 03 3/3/3 1/1/1*3/3/3 1/1/1*1/1/1*3/3/3 2/2/2*3/3/3 1/1/2*1/1/1*1/1/2* Granulationscored 03 0/0/0 0/0/0 0/0/0 0/0/0 0/0/0 0/0/0 0/0/0 0/0/0 0/0/0 0/0/0 0/0/0 Necrosis scored 03 2/2/2 1/1/1*3/3/3 2/2/2 2/2/2 3/3/3*2/3/3 3/3/3*2/2/2 2/2/2 2/2/2 Number of inammatory cells 150/ 169/ 185 120/135/ 154* 170/ 189/ 205 135/148/ 164* 145/ 159/ 172* 190/219/ 225* 160/ 180/ 195 180/189/ 195* 143/153/ 169* 133/140/ 163* 130/158/ 170 * Intestinal obstruction scored 03 1/1/1 0/0/0*1/1/1 0/0/0*0/0/0*1/1/2 1/1/1 1/1/1 0/0/0*0/0/0*0/0/0* Adhesions scored 07 1/1/1 0/0/0*1/1/1 0/0/0*0/0/0*1/1/2 1/1/1 1/1/1 0/0/0*0/0/0*0/0/0* BPC 157 (10 g/kg, 10 ng/kg), L-NAME (5 mg/kg), L-arginine (100 mg/kg) were applied alone and/or combined while controls received an equivolume of saline (5 ml/kg) intraperitoneally