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I would suggest that you need to read all of the studies before you reach a conclusion

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Interactions between resident immune cells in the CNS and peripheral immune cells through immune molecules render inflammation systemic, ultimately leading to the dysfunction of neuromuscular junctions, damage to motor neuron axons, and motor neuron death [255]

We've all heard of them, and we all probably at least have some idea what they are

CagriSema and Retatrutide are investigational compounds and are not FDA-approved for human treatment as described here