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The primary molecular actions relevant to skin are: modulation of TGF- signaling (upregulating TGF-1 for collagen I/III synthesis while suppressing TGF-2 to prevent scarring), decorin upregulation for orderly collagen fibril assembly, MMP suppression paired with TIMP upregulation to preserve ECM integrity, and copper-dependent lysyl oxidase activation for collagen crosslinking

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Potential risks and contraindications As mentioned before, these items are not usually sold by healthcare professionals, so some may be contraindicated if you are breastfeeding or pregnant, have digestive issues (such as irritable bowel syndrome, Crohn's disease, or ulcerative colitis), take certain medications (including birth control and blood thinners), or have kidney or liver disease