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By blocking this enzyme, researchers can observe a significant shift in cellular methyl-donor availability

The coding region was cloned into a modified pETM-11 bacterial expression vector (EMBL Heidelberg) which was derived from a pET-24d(+) vector (Novagen) by insertion of a tobacco etch virus (TEV) protease cleavage site following a N terminal hexa-histidine and protein A tag

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Behav Brain Res 321:7986 Yao C, Zhang J, Liu G, Chen F, Lin Y (2014) Neuroprotection by (-)-epigallocatechin-3-gallate in a rat model of stroke is mediated through inhibition of endoplasmic reticulum stress

Journal of Clinical Investigation, 84 , 863875