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University of Toronto, Masters thesis.

Although the body has the ability to destroy free radicals naturally, a build-up can occur as a result of an unhealthy diet, ageing, mental stress, sun exposure, smoking and exposure to environmental pollutants

When GHRP-2 binds to GHSR-1a in the hypothalamus, it is theorized to trigger a signal transduction cascade that could lead to increased production of the hunger-inducing neuropeptide, Neuropeptide Y (NPY), and Agouti-related peptide (AgRP), both of which are believed to play significant roles in energy homeostasis and appetite regulation

GPX3 is directed to extracellular compartments and is excreted from various tissues in contact with body fluids

As of 2021, studies on glutathione's skin-lightening effects are sparse, small-scale, and often not peer-reviewed, limiting the ability to generalize results