Key Functions of Glutathione: Antioxidant Defense Neutralizes free radicals and reactive oxygen species (ROS), protecting cells from oxidative stress
Liu Y, Mo L, Goldfarb DS, Evan AP, Liang F, Khan SR et al (2010) Progressive renal papillary calcification and ureteral stone formation in mice deficient for Tamm-Horsfall protein
Author contributions HH: Conceptualization, Methodology, Writingoriginal draft, Writingreview and editing
France : Groupe Robert Laffont
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8 The mechanisms of APAP-induced cell death, which apply to both animals and humans, include the formation of the reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI) by cytochrome P450 2E1 (Cyp2E1), depletion of hepatic GSH, and protein adduct formation, primarily in mitochondria