Kassir M
Store in a cool, dark place away from direct sunlight and out of reach of children
A greater concentration of free radicals may lead to cell damage, causing wrinkles, dull skin, and lower energy levels associated with aging
At the molecular level, 5-amino-1MQ functions as a competitive inhibitor of NNMT, demonstrating remarkable potency with an IC of 1.2 0.1 M under standard assay conditions (50 M SAM, 100 M nicotinic acid). This represents a dramatic 10-fold improvement over the parent compound 1-methylquinolinium, achieved through strategic amino group substitution that enhances binding affinity to the NNMT active site. The compound's mechanism centers on preventing the methylation of nicotinamide to 1-methylnicotinamide (1-MNA), thereby preserving nicotinamide for recycling back to NAD+ through the salvage pathway. This intervention effectively blocks what researchers have termed the "NNMT metabolic drain" a process that simultaneously depletes NAD+ precursors and consumes cellular methylation capacity
doi: 10.1152/ajpendo.2001.280.1.E40
Medical-Grade Vial Packaging The filtered solution is aseptically transferred into sterile, depyrogenated 10 mL glass vials, each sealed with tamper-evident caps and sterile rubber stoppers
