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CJC-1295 therapy with DAC is used less frequently due to concerns about sustained GH elevation potentially disrupting normal feedback mechanisms

Indeed, increasing evidence demonstrates that the antiretroviral drugs used for HIV treatment have toxic effects resulting in various cellular and tissue pathologies

Gopinath, P

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62 , e202300379 (2023)

Acid reduction is critical to the health of mitochondria, which require antioxidant systems to neutralize oxidative phosphorylation, as mitochondrial DNA is more susceptible to oxidative damage than nucleus DNA