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Laminin-5 and MMP upregulation TB4 induces expression of matrix metalloproteinases (MMP-2, MMP-9) that remodel extracellular matrix during healing (Malinda 1999 J Invest Dermatol)

4:389-398 (2013) Hajar-Azhari S, Wan-Mohtar W, Ab Kadir S, Rahim MHA, Saari N

Scientists at the University of California San Diego found not only that fungi thrived in the intestines of mice exposed to high doses of alcohol, but that the inflammation created by the spawning fungi sped up the onset and progression of alcohol-related liver disease (Nonalcoholic fatty liver disease affects up to a third of Americans, taking a toll on our collective health

Cell death & disease 4 , e642, (2013)

Route reported Subcutaneous injection most common