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Reduction of oxidative stress: Effectively reduces oxidative stress, facilitating the regeneration and strengthening of tendons and joints

2,2-Bipyridine (Bpy) units can in principle be used as bridges to interconnect metal centers in a well-defined spatial arrangement

The multifunctional enzyme encoded by the MTHFD1 gene converts 5,10-methylene-THF to 10-formyl-THF which is required for the synthesis of the purine nucleotides

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doi: 10.1172/jci.insight.154585 87 PietrzakALecewicz-ToruBUrbanJ

Van Haren RM, Mehran RJ, Correa AM, Antonoff MB, Baker CM, Woodard TC, Hofstetter WL, Mena GE, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC