I also know people that are taking oral versions of this and I think that science has shown that thats completely useless
Mechanistic: Laboratory/preclinical evidence suggesting a plausible effect
In aged Wistar rats with documented age-related melatonin decline: Epitalon treatment restores AANAT mRNA and enzyme activity toward young-animal levels Nocturnal melatonin amplitude is increased (RIA/ELISA measurement in plasma and pineal tissue) Circadian locomotor rhythm amplitude is partially restored in aged rodent models (wheel running actograms) Core clock gene expression (BMAL1, CLOCK, PER1/2, CRY1/2) shows partial restoration in Epitalon-treated aged tissues GHK-Cu has no documented pineal or circadian mechanism
Use 23 times a week
What was the retatrutide starting dose in the trials
Solutions: Extend trial to 6 months before concluding inefficacy (some benefits take longer), increase dosing within safe ranges if using lower end, switch peptides (try Cerebrolysin if using BPC-157, or vice versa), add comprehensive eye exam to rule out progression versus peptide failure, consider peptides preventing worsening rather than producing improvement, discontinue if truly no benefit after 6 months rigorous trial