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In contrast, increased cell death was consistently observed across various lymphoid cell types, including tumor cells, underscoring that, within 3D gels, cell death, rather than cell cycle arrest, impedes lymphoid cell growth

Ruiz et al., 2022

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Myoinositol (B8) and D-chiro-inositol: This is naturally occurring in almost every tissue that is involved in insulin and gonadotropin signaling, affecting follicle maturation

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While this is an established technique 84,85 , this approach is less physiologically relevant than orally administered glucose, as it bypasses incretin hormone signaling that could significantly impact insulin secretion and glucose homeostasis 86