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Hanasaki Y, Ogawa S, Fukui S

Heme oxigenase is part of the system which regulates the integrity of endothelial cells and which also regulates oxidative stress

All patients underwent plasma biomarkers dosage, brain-MRI with detection of SVD markers alone and CSVD score and were stratified according to APOE(APOE3 = 26;APOE4 = 24)

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