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In line with this finding, Erastin significantly reduced GSH-related metabolites (Cysteine, Cys-Gly, GSSG) but increased glutamine uptake in LDHB KD A549 cells ( Figure 4c, Supplementary Figure 8a, b, ), suggesting that combined inhibition of LDHB and SLC7A11 increased glutaminolysis

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It is widely studied for its potential roles in tissue regeneration, cellular repair, angiogenesis, and gastrointestinal protection within controlled laboratory settings