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The assay includes a control test tube to ensure the accuracy of the GPx activity measurements and address potential interferences from other thiols and sample components

SARS-CoV-2 mainly destroys pulmonary surfactant-secreting type II alveolar cells (Wang et al., 2021a), that normally decrease the air/tissue surface tension and block TLR4 in the lungs, promoting ARDS and inflammation

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Because it depends on the regulation of certain nuclear receptors, induction of CYP3A and P-gp occurs with a delay (95, 96)

Traditional fatigue assessment methods rely on surveys or physiological signal measurements, which often fail to provide real-time monitoring and are limited by patient discomfort

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