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Acknowledgements This work was funded by NIH R01CA163591, NIH DP1DK113643, Ludwig Cancer Research and Stand Up to Cancer SU2CAACR-DT-20-16 to J.D.R

Patients with Pre-Existing Lipid Disorders Anyone with familial hypertriglyceridemia, familial combined hyperlipidemia, or a baseline fasting triglyceride level above 300 mg/dL before starting isotretinoin should have a formal lipid management plan in place before initiating the retinoid