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Nature 583 (7816), 441446

As a selective substrate site-targeting inhibitor of nicotinamide N-methyltransferase (NNMT) the cytosolic enzyme responsible for the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor 5-Amino-1MQ is studied as a tool compound for investigating NNMT enzyme activity, NAD salvage pathway interactions, and methylation pathway dynamics in controlled in-vitro experimental systems

Because of its defined molecular profile, the compound is frequently used in laboratory studies examining metabolic regulation and biochemical processes

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AOD9604 targets fat-rich areas and promotes fat breakdown without disturbing the overall metabolic profile