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Histone H3K9 demethylase KDM3B, as a potential epigenetic regulator of ferroptosis, can upregulate the expression of the SLC7A11 gene and inhibit ferroptosis [67]

This indicated the protective role of alogliptin in atrial fibrosis-induced heart failure [28]

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It has been possible to map the incretin function in humans in some detail owing to the availability of receptor antagonists for both hormones, namely exendin 9-39 for the GLP-1 receptor and the amidated GIP fragment GIP 3-30 amide for the GIP receptor [2]