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While many of the key regulators of this pathway remain largely unknown, recent studies have identified glutathione peroxidases, particularly glutathione peroxidase 4 (GPX4), as antioxidant enzymes that can prevent lipid peroxidation using reduced glutathione (GSH) as a co-factor 9,10

Increased eNOS activity is associated with the reduced binding to Cav-1 17,18

Experimental obstructive cholestasis: the wound-like inflammatory liver response

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