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Monitoring Required: Observe patients for any side effects, particularly if receiving high doses or prolonged treatment

Despite the limitations of the dataset, the available information did provide some insights into the relationship between GH and sleep in children with GHD, allowing us to answer the individual questions listed in Figure 1

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During the process of apoptosis, release of excessive quantity of intact nucleosomes has been suggested to be a source of nuclear antigens that drive an immune response, inducing anti-DNA and anti-histone antibody production [93,94]

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