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Additionally, RStudios R version 4.0.2 was used to create a debiased sparse partial correlation (DSPC) algorithm network, clustering heatmap, and variable importance projection (VIP) score

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The Wnt/-catenin signaling pathway target genes Lgr6 , lef1 , and Tcf7 (Lien et al., 2014) showed elevated expression, while the expression of Wnt inhibitors Sfrp4 , Sfrp5 , and Dkk1 (Huyghe et al., 2015

Severe deficiency: For extreme insufficiency and blood health problems like pernicious anemia, treatments with 1000 2000 mcg per day are prescribed

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