Vigorous shaking creates foam, introduces air, and can physically damage the peptide through agitation-induced aggregation
Xue et al., 2004a
not that it hasn't been thick for three years already if not more, but whatever
Studies have shown that 510% weight loss can improve insulin resistance, dyslipidemia, glucose tolerance, menstrual function, ovulation, and pregnancy
For patients with severe kidney disease, impaired renal function can affect how excess B12 is cleared from the body
You may have a deficiency if you are vegan, if you have other health conditions which mean you are unable to absorb it properly such as pernicious anaemia, you take disruptive medications such as antacids or other lifestyle factors such as alcohol intake