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roGFP2-Orp1 fluorescence ( ex1 =400/10 nm, ex2 =482/16 nm, em =530/40 nm) was measured at 37C and 5% CO 2 for 19 h, using a Clariostar microplate reader (BMG Labtech)

Delayed Treatment: Vitamin B12 deficiency left untreated for longer than 3 months may cause permanent spinal cord and nerve damage

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Programmed cell death and Bcl-2 protection in very low oxygen

Studies using the GABA analog in Fmr1 knockout mice demonstrated corrections in hyperactivity and modulation of altered sensory-motor gating, measured as increased prepulse inhibition following acute treatment, by enhancing the activity of extrasynaptic GABA receptors, thereby improving anxiety, aggression, and repetitive behavioral abnormalities in FXS mice (71)

Yao et al., 2002)