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They can be a cause for excessive bleeding for those taking anticoagulant medication and may exacerbate symptoms if taken together continuously in large doses

For persistent or concerning symptoms, reduce dose or frequency and observe

TNF produces inflammation by chemokines, cytokines, metalloproteinases, prostaglandin E2, and adhesion molecules

Sardu, C

Figure 1 By carefully adjusting factors such as substrate stiffness, topographical cues, and fluid flow patterns, OoC technology enables the incorporation of one or more cell types within a single or interconnected device effectively mimicking various organ functions in a controlled environment (45)