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Research reveals that some chemotherapy-induced senescent cells may initially contribute to administration efficacy through SASP-mediated immune activation, but their persistence can promote tumor recurrence and administration resistance

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Through SASP, senescent cells may permanently confer a state of stemness in neighboring cells and thereby impair tissue function and renewal, an effect which we recently described in the senescence-stem lock model for aging (de Keizer, 2017)

Using tissue from donors, the team observed that cells in the nucleus pulposus, a jelly-like structure at the center of intervertebral discs, had a lower amount of this peptide receptor when degeneration increased

GHK-Cu focuses on copper-mediated collagen synthesis and antioxidant activity valuable for skin and wound research, but absent the vascular and neuroprotective dimensions of the compounds profile

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