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Altered skeletal muscle metabolic pathways, age, systemic inflammation, and low cardiorespiratory fitness associate with improvements in disease activity following high-intensity interval training in persons with rheumatoid arthritis

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Within cellular contexts, autophagy can function as a protective compensatory mechanism in response to elevated iron levels, thereby mitigating cell death associated with oxidative stress and other detrimental factors [115]

Dringen R, Hirrlinger J