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Tsai et al (1994, 1996) reported that homocysteine is mitogenic to both human and rat aortic smooth muscle cells by stimulating the induction of cyclin A protein expression

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That is important, because it confirms that VEGFR2 is not just one of many mechanisms, but truly a causal pathway

The target tissue is the GI tract itself, where luminal concentration is the relevant variable (BPC-157 for gastric mucosa, certain GI motility peptides)