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High smoking rates among people with mental health conditions are the single largest contributor to their 10 to 20-year reduced life expectancy

The pleiotropic effects of tobacco smoke on the immunostimulatory function of DCs are further illustrated by a study reporting a diminished capacity of DCs from cigarette smoke-exposed mice to induce IL-2 production by T cells, which was associated with a decreased antigen-specific T-cell proliferation in vivo

Signs of use may be visible

Johnny Perez-Gonzalez contributed to this story

When talking about the previous period, if you would like to see what the situation on this issue was some years ago, you can take a look at 7 Cigarette Brands with Lowest Tar and Nicotine for 2017

At SHC, we found that ~20% of patients exhibited implausible transitions in smoking status in their longitudinal smoking history data