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Most of the product licences, or marketing authorities as they are called in the UK, for hydroxocobalamin date from the 1990s when the requirement for evidence was different than it is now

Alcohol and Thiamine (Vitamin B1) Deficiency: Brain Fog, Neuropathy, and Wernicke Risk Thiamine deficiency is one of the most clinically significant consequences of alcohol use , particularly because of its impact on the brain and nervous system

Allow ~5 doses per vial