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These proteins are implicated in mitosis, fatty acid metabolism, p53-dependent apoptosis and complex I of the mitochondrial respiratory chain, respectively ( Supplementary Table S1 )

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Supporting a dominant role for diet composition in establishing the Firmicutes : Bacteroidetes ratio, previous work has shown that mice maintained on a high-fat diet had a similar cecal Firmicutes : Bacteroidetes ratio to those maintained on a high-carbohydrate diet 77

The role of the UPS in the regulation of LD proteins will be reviewed, (Figure 1) and a more in-depth review on the regulation of the LD proteome can be found by Bersuker et al

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Vitamin B12, also known as cobalamin, is a molecule that isnt easily absorbed into our systems