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Recently, a high-resolution crystal structure of phosphinic pseudopeptide inhibitor 45 (DG046) in the closed-conformation of ERAP1 was disclosed (Giastas et al., 2019b) and a mechanism for antigen peptide selection by ERAP1 presented ( In 2015, Papakyriakou et al

It plays an essential role in energy metabolism by transporting long-chain fatty acids into the mitochondria, the powerhouses of your cells

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