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Prog Neuropsychopharmacol Biol Psychiatry 26(3):473480 Rostami-Hodjegan A, Kroemer HK, Tucker GT (1999) In-vivo indices of enzyme activity: the effect of renal impairment on the assessment of CYP2D6 activity

in this age group, male lifetime smokers with and without AMI were equally likely to be current smokers

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While they can be effective, they come with risks

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In an early clinical study, Dyke et al (81) found that in males only, DNA adducts in gastric tumor tissues from smokers were significantly higher than in those from non-smokers