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The elevated ROS levels impaired mitochondrial function and morphology and reduced hyphal development and biofilm formation

Role of ferroptosis in PD Ferroptosis is regulated by multiple interconnected pathways, including the GPX4/GSH system, iron and lipid metabolism, the NRF2 signaling pathway and mitochondrial function, in PD (Fig

MIF inhibitor ISO-1 alleviates severe acute pancreatitis-associated acute kidney injury by suppressing the NLRP3 inflammasome signaling pathway

Enhanced collagen synthesis and connective tissue support [8]

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Selective transport of GSH across the ER membrane has been shown in mammalian liver microsomes (Banhegyi et al , 1999), and into the sarcoplasmic reticulum of skeletal muscle (Banhegyi et al , 2003)