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Potential Benefits: A Summary Based on the available (predominantly preclinical) literature, the following potential benefits have been identified: Risks & Safety Considerations Known & Reported Side Effects Because large-scale human trials are lacking, our understanding of the side effect profile is limited

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Lack of Awareness: The Pernicious Anaemia Society and other patient advocacy groups have highlighted that some GPs and nurses may not be fully up-to-date on the latest guidelines or may misinterpret them

5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase, an enzyme highly expressed in adipose tissue that regulates NAD+ metabolism and cellular energy balance

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