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Interestingly, in WD not only copper, but also iron metabolism is affected

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3.7.2 Ferroptosis and autosomal dominant polycystic kidney disease Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease, caused by mutations in either the PKD1 or PKD2 gene, and is characterized by the development of multiple renal cysts

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doi: 10.1016/j.biopsych.2016.06.017 52 KaufmanMJJanesACHudsonJIBrennanBPKanayamaGKerriganARet al