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Vitamin B12 is crucial for several physiological processes, including: Red blood cell formation deficiency leads to megaloblastic anaemia, characterised by large, immature red blood cells Neurological function B12 is required for myelin synthesis and nerve health DNA synthesis essential for cell division and growth Without adequate B12, patients may develop symptoms such as fatigue, pallor, shortness of breath, glossitis (sore tongue), paraesthesia (pins and needles), and in severe cases, neurological complications including peripheral neuropathy, ataxia, and cognitive impairment

For most insulin syringes, this is approximately 0.5 to 1 unit of volume

Thus far, the molecular effects of IFIH1 variants associated with T1D have mostly been reported in human PBMCs and mouse models

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It has been the subject of hundreds of published preclinical studies examining its effects across multiple tissue types

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