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Clin Gastroenterol Hepatol 4:387394
Intracellular zinc trafficking: zinc transporters Zinc is not uniformly distributed within the cell
Renal water reabsorption-associated proteins, including UT-A1 and AQP2, regulated by PKC- via phosphorylation of UT-A1 at Ser494 and AQP2 at Ser256 or dephosphorylation of AQP2 at Ser261 ( CHI leaves could quickly and markedly alleviate diabetic polyuria and polydipsia in a dose-dependent manner within 2 weeks post-treatment in diabetic mice (Figures 2A, B), and the mechanism involved in the enhanced renal water reabsorption associated protein UT-A1 and the increased trafficking of AQP2 to the apical plasma membrane (Figures 2H, I)
hence, it is more preferable than cyanocobalamin for the treatment of vitamin B12 deficiency (1,2,3,4)
Norton & Company, 2012)