The sensitivity of PR3-ANCA was comparable to that of atypical perinuclear ANCA, but its specificity was significantly higher, suggesting that PR3-ANCA could serve as a potential biomarker for extensive UC [16, 33, 34]
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doi: 10.1007/112_2018_11 527 SinghMSinghN
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Central to this approach are degrons, short amino acid motifs, typically 610 residues in length, that mark proteins for recognition by E3 ubiquitin ligases