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5 Am J Physiol Gastrointest Liver Physiol (PubMed) Slifer 2021Slifer et al

Although GHK-Cu and Pal-GHK have been of interest as effective peptides to be incorporated in the anti-wrinkle products, there is a surprising absence of clinical studies using them

This is why ex vivo findings need to be confirmed in human trials which subsequent studies like the 2016 GHK peptide clinical trial and the 2021 copper tripeptide serum trial have done

Energy, mood, and concentration levels often improve within 1 to 3 days after the injection

doi: 10.1007/BF00423298

Since growth hormone release is regulated by the hypothalamus and pituitary gland, any influence on these neural systems might indirectly affect testosterone production