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Summary: Vitamin B12 supplementation does not directly cause joint pain, and no established causal link exists in medical literature

Down-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatment

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This has led some people to look into other options that may support healing rather than simply symptom control

Studies document accelerated collagen remodeling and improved structural recovery in Achilles tendon injuries PMID: 25415472