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Six to eight month old C57BL/6 mice were injected with 400,000 B16-F10 cells in 200 l PBS by tail vein injection and subsequently received daily intraperitoneal injections of either D-Nle-X-Cys-NH(CH 2 ) 5 CONH 2 (10 g/kg and 100 g/kg) or a PBS vehicle control