Gene knockout was performed using the one-step inactivation method of Datsenko and Wanner [32]
Adults with a body mass index (BMI) of 30 or greater Adults who are overweight with a related condition such as type 2 diabetes, high blood pressure, or elevated cholesterol Patients seeking a clinically supervised, medication-supported weight management approach alongside diet and lifestyle modifications Dr
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Proc Natl Acad Sci USA 103:94769481 Yang QH, Botto LD, Gallagher M, Friedman JM, Sanders CL, Koontz D et al (2008) Prevalence and effects of gene-gene and gene-nutrient interactions on serum folate and serum total homocysteine concentrations in the United States: findings from the third National Health and Nutrition Examination Survey DNA Bank
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