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84 The overexpression of circHECTD1 leads to increased expression levels of p62, ATG5, and ATG9 via the inhibition of miR-182-5p, which activates AMPK/mTOR signaling and reduces colonic injury and inflammation by promoting autophagy

Al-Hakeim HK, Al-Rubaye HT, Almulla AF, Al-Hadrawi DS, Maes M

Insulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1Egr1ATGL-mediated pathway

Additional genetic polymorphisms occurring in choline and one-carbon metabolic pathways may alter the dietary requirement for choline and thus increase the likelihood of developing signs of deficiency when choline intake is inadequate (9, 20, 21)

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