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Long-term treatment of glucocorticoids is associated with oxidative brain damage in primates, which has been demonstrated (113)
Furthermore, animal research has found that extremely high doses of alpha-lipoic acid may promote oxidation, alter liver enzymes, and place strain on liver and breast tissue (38, To date, very few studies have looked at the safety of alpha-lipoic acid in children and pregnant women
Gujral JS, Knight TR, Farhood A, Bajt ML, Jaeschke H
A full discussion of risks and benefits is appropriate
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