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In patients with retinal vein occlusion, elevated serum oxidative stress marker levels, such as MDA, 8OHdG or H 2 O 2 were detected, while scavenging enzymes for ROS, such as SOD, were decreased [317]

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In mice, glutathione administration has been shown to improve cognitive decline and depressive-like behaviours, even as the supplement's effects in humans are yet to be determined conclusively