20 Systematic reviews: Oral vitamin B 12 replacement for the treatment of pernicious anemia 21 Relevant articles were identified by PubMed search from January 1, 1980 to March 31, 2016, focusing on patients with pernicious anemia
Avoid alcohol and caffeine before the injection
Key Takeaways Vitamin B12 is vital for neurological function and DNA synthesis
the product information notes that refrigeration can cause a color change (darker yellow) which does not affect safety or effectiveness
Each mL of sterile aqueous solution contains: Cyanocobalamin (B12)..........3000 mcg With sodium chloride 0.22% w/v, ammonium sulfate 0.1% w/v, citric acid 0.01% w/v, sodium citrate 0.008% w/v, and benzyl alcohol 1.0% v/v (preservative)
[12] A further complication of severe deficiency is the neurological complex known as subacute combined degeneration of spinal cord