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In clinical trials, most participants receiving lecanemab or donanemab transitioned from being amyloidpositive to being amyloidnegative after 18 months of treatment (called treatmentrelated amyloid clearance or TRAC)

In biochemical systems, actin-binding peptides derived from thymosin beta-4 function as regulators of cytoskeletal assembly by influencing the equilibrium between monomeric and filamentous actin

Neurotransmitter modulation Semax also appears to modulate key neurotransmitter systems particularly dopamine and serotonin

References Alfredsson, L., Armstrong, B

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