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Diabetic retinopathy involves inflammatory mediators promoting vascular damage

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This upregulation leads to an increased expression of lipogenic genes, including sterol regulatory element-binding proteins (SREBP1c) and diacylglycerol acyltransferase-2 (DGAT2), which suggests that miR-370 provides a further point of regulation of this pathway 86

These phosphorylated residues serve as docking sites for adapter proteins that initiate downstream signaling