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It has been demonstrated that numerous proteins critical for the structure and function of neurons, astrocytes, and synapses undergo O-GlcNAcylation [29]

doi: 10.3390/ijms21124229 158 ShangKHeJZouJQinCLinLZhouLQet al

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Compared to mAChRs, nAChRs have a reduced affinity for the natural agonist ACh, which suggests that they may be involved in negative feedback mechanisms linked with growing levels of ACh

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